Senior Scientist, Computational Chemistry
Hands-on computational chemist applying ligand/structure-based methods to drive drug discovery efforts in San Diego.
On-site • San Diego, CA, USA- Full Time
- $137,600 – $172,000/year
- Min. 5 YOE
Iambic Therapeutics
15 open rolesLast updated May 1, 2026 at 6:49 AM UTC
All open jobs at Iambic Therapeutics
Browse the full live job inventory for Iambic Therapeutics. This page is focused on current openings, while the overview tab highlights role groups and hiring patterns.
15 open positions
Software Engineer I/II, Machine Learning
ML software engineer designs production ML workflows and GPU-accelerated services for drug discovery with CI/CD and observability.
- Hybrid • Boston, MA, USA
- Full Time
- $129,600 – $190,000/year
- Min. 5 YOE
Senior Clinical Trial Manager, Clinical Operations (EU)
Operational lead for complex, multi-regional oncology trials with end-to-end trial leadership and vendor oversight.
- Full Time
- Min. 7 YOE
Software Engineer II, Machine Learning Systems & Productization
Translate experimental research code into maintainable, well-structured, and reusable systems.
- Remote • United States
- Full Time
- Min. 8 YOE
Sr/Principal Scientist, Computational Chemistry
Lead computational chemistry efforts across hit identification, lead optimization, and candidate selection in drug discovery using SBDD, co-folding, and ML-augmented workflows.
- On-site • San Diego, CA, USA
- Full Time
- Min. 5 YOE
Sr Associate Scientist I or II, Medicinal Chemistry
Senior associate scientist with organic synthesis expertise driving hit identification, lead optimization, and data-driven decisions in medicinal chemistry.
- On-site • San Diego, CA, USA
- Full Time
- Min. 5 YOE
Associate Director/Director, Biology (Oncology Drug Discovery)
Lead oncology drug discovery programs, drive cross-functional biology plans, and integrate AI/ML-enabled data interpretation for decision-making.
- On-site • San Diego, CA, USA
- Full Time
- Min. 12 YOE
Director, Clinical Supply Chain- CMC
Lead end-to-end clinical supply strategy and execution for small molecule programs from first-in-human through clinical phases.
- Remote • United States
- Full Time
- Min. 15 YOE
Research Scientist II/Sr, Analytical Purification
Analytical purification specialist leads chromatographic purification workflows, optimizes throughput, and supports ADME/DMPK assay design in a drug-discovery context.
- San Diego, CA, USA
- Full Time
- Min. 2 YOE
Director/Senior Director, Medicinal Chemistry
Medicinal chemistry leader directing drug discovery programs, cross-functional teams, and AI/ML collaboration to accelerate design–make–test cycles.
- On-site • San Diego, CA, USA
- Full Time
- Min. 15 YOE
Principal Scientist, Medicinal Chemistry
Medicinal chemist leading lead identification, SAR-driven optimization, and AI-enabled design collaboration.
- On-site • San Diego, CA, USA
- Full Time
- Min. 8 YOE
Research Scientist II/Senior, Discovery ML
Lead development of ML models for drug discovery, collaborating with chemists and biologists to drive high-throughput design-make-test cycles.
- On-site • San Diego, CA, USA
- Full Time
- Min. 3 YOE
Director, Drug Product Development
Lead formulation and process development for small molecule programs from late discovery through clinical phases, ensuring scalable, patient-centric drug products and regulatory-ready CMC documentation.
- On-site • San Diego, CA, USA
- Full Time
- Min. 10 YOE
Associate Director, DMPK
Leads design and execution of DMPK strategies to support discovery, preclinical programs, and regulatory submissions.
- On-site • San Diego, CA, USA
- Full Time
- Min. 12 YOE
Head of Quality Assurance
Leads Quality Systems and Compliance design/implementation of a QMS across global clinical programs.
- Remote • United States
- Full Time
- Min. 10 YOE